K. Luan Phan MD

Professor of Psychiatry
Associate Head for Clinical Services
Associate Head for Clinical and Translational Research
Director of the Mood and Anxiety Disorders Clinical and Research Programs

Dr. K. Luan Phan is the UI CDR Endowed Professor, Director of the Mood and Anxiety Disorders Research Program (MADRP) and Associate Head for Clinical and Translational Research in the Department of Psychiatry at the University of Illinois at Chicago.  He is also Chief of NeuroPsychiatric Research and a VA Research Scientist at the Jesse Brown VA Medical Center.  He has a longstanding commitment to translate discoveries from affective and cognitive neuroscience to improve our understanding and treatment of anxiety and mood disorders.

Lab/Research Program website: https://www.psych.uic.edu/research/lab-directory/madrp-phan-lab

Patient-oriented research in his interdisciplinary Research Program crosses both UIC and the VA and studies variations of psychopathology and health from an affective neuroscience perspective (phan Lab). His team understands that emotions have a powerful role in tuning our perception, imbuing our experience, guiding our decisions, and shaping our actions. As such, they believe that anxiety, fear, depression, addiction, obsessions and compulsions can be understood along dimensions of emotion that evolve over the lifespan and fluctuate with stress. They use neuroscience measures and methods to study the emotional brain and its readouts in the laboratory and the real world, and marry this approach with psychopharmacology, neuromodulation and intervention trials. The team primarily uses magnetic resonance imaging (fMRI, DTI, sMRI), electroencephalography (EEG) of event-related potentials (ERP), and other psychophysiological tools to assess brain circuit function as they relate to emotion, affect regulation and motivation. Their work seeks to better understand the neuropathophysiology and course of psychopathology, and to innovate strategies to prevent and treat more patients better and faster and keep them well for longer periods of time.

Dr. Phan received his medical degree from the University of Michigan in Ann Arbor and received psychiatry residency and research track training at the Western Psychiatric Institute and Clinics at the University of Pittsburgh and at the University of Michigan Hospitals and Clinics.  Prior to joining the faculty at the University of Illinois at Chicago in February 2012, he was Associate Professor in the Department of Psychiatry and Neuroscience Program at the University of Michigan and Chief of the Mental Health Clinic at the Ann Arbor VA Healthcare System.

Dr. Phan has been awarded the Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor bestowed by the United States government on outstanding scientists and engineers in the early stages of their independent research career. Dr. Phan’s research has been consistently funded by the National Institutes of Health, Veterans Affairs, and Department of Defense over the past 15 years.  He has over 200 peer-reviewed publications, in journals such as Archives of General Psychiatry, Biological Psychiatry, American Journal of Psychiatry, Neuropsychopharmacology, Proceedings of the National Academy of Sciences, Journal of Neuroscience, and Nature Reviews Neuroscience. Dr. Phan has served as editor and on editorial boards for several journals and peer reviewer on several NIH, DoD, and VA study sections. He has been a member of the Scientific Council of the Anxiety and Depression Association of America, and the Scientific Program Committee of the Society of Biological Psychiatry. He has been selected as a Felllow of the American College of Neuropsychopharmacology (ACNP).

Research Themes:

  1. Functional Neuroanatomy of Emotion, Cognition, and Motivation
  2. Functional Neuroanatomy Anxiety, Mood and Addiction Disorders
  3. Brain Mechanisms and Predictors of Treatment Response in Mood and Anxiety Disorders
  4. Functional Neuroimaging of Drug Effects on Emotion and Cognition

PHONE:(312) 355-5954EMAIL:klphan@uic.edu