Everyone experiences depression a bit differently. At UI CDR, we develop treatment methods for the individual, not the disorder. To this aim, we explore a range of methods to meet and treat patients where they are at from alternative treatments to streamlining pathways, UI CDR is delivering tailored treatment to everyone we serve.

UI CDR uses imaging technology to distinguish PTSD from other illnesses, predict how well a patient will respond to certain medications, and guide physicians to the best pharmacological options. We develop mental health strategies for children that bring the clinic to the community and deliver behavioral interventions in everyday settings like schools, playgrounds, and home. We provide integrated models that provide screening and treatment for depression among pregnant and postpartum women seeking health care during their routine checkups.

To streamline this process for each individual in our care, UI CDR has established a symbiotic relationship between clinical practice and pioneering research. Our child and adolescent clinic influences renowned evidence-based treatment curriculums. Our Cognitive Behavioral Therapy program at the Adult Mood Disorders Clinic inspires apps, web-based treatment tools, and tablet interventions. Our research informs practice, our practice informs research and by integrating the two, we deliver research-informed, custom care.



Featured Article
In pursuit of precision medicine for PTSD

"Brain scans of war Veterans with posttraumatic stress disorder have led researchers to an area of the prefrontal cortex that appears to be a good predictor of response to treatment with SSRIs—the first-line drug treatment for PTSD. The findings, which came out online June 26, 2015, in the journal Neuropsychopharmacology, are hopeful news amid a new national push toward "precision medicine" in which doctors will tailor drug regimens and other treatments based on patients' individual gene profiles or other factors. President Obama announced the initiative earlier this year.

How to Address Rising Suicide Rates in the U.S.

Dr. Scott Langenecker, Associate Director of the UI Center on Depression and Resilience, was featured on WTTW’s news program Chicago Tonight to talk about the rising toll and what can be done to reduce the numbers and help people in crisis.

brain scan
Brain Scans May Predict Who Benefits from Antidepressants

Sending patients with depression to get a brain scan before going on antidepressants may help doctors determine whether or not antidepressants will be effective. UICDR Researcher Dr. Scott Langenecker's new study takes an important step toward individualized medicine for depression treatment.

Antidepressant side effects reported more by patients with panic disorder
Antidepressant side effects reported more by patients with panic disorder

Patients who take medication for depression report more side effects if they also suffer from panic disorder, according to a new study led by UIC researchers and published in the Journal of Clinical Psychiatry.

Patients with panic disorder report more antidepressant side effects, study finds

Patient reactions to antidepressants can vary greatly from one person to another.

Problem-solving leads to better lives for those with mood disorders

Using a multi-method approach to explore the relationship between mood and anxiety disorders, Stewart Shankman seeks answers to the nature and course of depression.

Medical school burnout: How to take care of yourself
Medical school burnout: How to take care of yourself

The pressures of medical school can have a major impact on students’ mental health and wellness. A group of medical students recently gathered to discuss these pressures and maintaining mental health during medical school.

Cognitive therapy, mindfulness may help with menopausal depression
Cognitive therapy, mindfulness may help with menopausal depression

Psychotherapy and mindfulness techniques could help many women who experience depression during menopause, according to a review of existing research.

Young Adults Who Had Depression Have 'Hyper-Connected' Brain Networks
Young Adults Who Had Depression Have 'Hyper-Connected' Brain Networks

Young adults who struggled with depression in adolescence appear to have "hyper-connected" networks in their brain, researchers are reporting.

Bipolar Disorder: Keys to Improving Compliance
Bipolar Disorder: Keys to Improving Compliance

Non-adherence to prescribed medication by patients with psychiatric disorders is one of the greatest challenges reported by clinicians: “Over the course of a year, about three-quarters of patients prescribed psychotropic medications will discontinue, often coming to the decision themselves.


Dr. Carbray holds her PhD (93) and Master of Science (88) degrees from Rush University, Chicago and ...

Scott A. Langenecker PhD

Dr. Langenecker is a clinical neuropsychologist, and neuroimaging specialist who focuses on the translational neuroscience of mood disorders. His goal is to contribute to work defining the neural circuits leading to the development and perseveration of depression and related mood disorders, as well as prediction of treatment response.